The Cranes of Uganda stunned the Pharaohs of Egypt with a 1-0 defeat in their Group E encounter in the 2018 FIFA World Cup qualifier at Mandela National Stadium in Kampala.
Tanzania-based Emmanuel Okwi scored the decisive goal in the 52nd minute to hand the Cranes an important win in the race to Russia 2018 and ensured they move top of the table with 7 points with Egypt second on 6 points.
It is a first win for Uganda over Egypt since 1965.
The last time the two met competitively was at the Africa Cup of Nations earlier this year in Gabon with Egypt emerging as winners.
The win puts Uganda in pole position but throws the group open ahead of the remaining matches.
The two teams will clash in Alexandria on Tuesday for the corresponding fixture as the race to Russia heats up.
Ghana, who has a single point, play their third qualifier on Friday against visiting Congo Brazzaville who are bottom of the group with no point.